Dihexa Reconstitution Calculator
Enter the amount you want to measure. The vial buttons will highlight which vial strengths create cleaner syringe-unit measurements.
What amount do you need?
Type the target amount, then choose mg or mcg. Example: 2mg or 500mcg.
Syringe size:
Possible vial strengths:
Best Match
Good Match
Usable
Harder to Measure
Example Dihexa Titration Schedule
| Parameter | Details |
|---|---|
| Dosage (Anecdotal / Preclinical) | 5–10 mg/day (cognitive enhancement); 10–20 mg/day (neuroregeneration) |
| Route | Oral (capsule or solution) |
| Frequency | Daily |
| Cycle Length (Anecdotal) | 8–12 weeks, followed by reassessment |
| Half-life (Preclinical) | ~12.68 days (intravenous); ~8.83 days (intraperitoneal) |
| Reconstitution (For Research Only) | Sterile water (≥100 µg/mL) |
| Important Notes | Orally active; crosses the blood-brain barrier |
| Safety (Critical) | Research chemical. No human trials. Theoretical cancer risk due to c-Met activation |
| Legal (Critical) | Research compound; not FDA-approved; not approved for human use in the US/EU |
Possible vial strengths:
What Is It?
Dihexa
Angiotensin IV-derived peptide in cognition research.
Bacteriostatic Water
Sterile water containing a bacteriostatic preservative, commonly used when preparing multi-use research vials.
How To Mix Dihexa
1
CleanUse alcohol swabs to clean the tops of both vials.
2
Draw BAC WaterDraw the selected amount of bacteriostatic water.
3
Inject SlowlyAdd the liquid slowly down the side of the vial.
4
Swirl GentlyDo not shake. Swirl gently until dissolved.
5
Store ProperlyStore as directed and protect from heat and light.
Best Practices & Common Mistakes
Best Practices
- Use sterile technique.
- Protect from light and heat.
- Store refrigerated when appropriate.
- Use clean syringe-unit math before measuring.
Common Mistakes
- Confusing milligrams with milliliters.
- Choosing an option with awkward decimal units.
- Using too little liquid for very small measurements.
- Shaking the vial aggressively.
Dihexa Storage & Handling
Lyophilized Powder: −20°C (−4°F) for long-term storage (up to 24 months). Refrigeration 2–8°C (36–46°F) for short-term use (up to ~3 months). Original sealed vial in the freezer is safest.
Reconstituted Solution: 2–8°C (36–46°F), use within ~7–14 days. Keep sealed, avoid light, and do not repeat freeze-thaw cycles.
Reconstituted Solution: 2–8°C (36–46°F), use within ~7–14 days. Keep sealed, avoid light, and do not repeat freeze-thaw cycles.
Frequently Asked Questions
Dihexa is a water-insoluble small molecule. It is insoluble in water and ethanol, with solubility reported in DMSO (30-100 mg/mL) and methanol (slightly). BAC water will not work; you must use anhydrous DMSO as the primary solvent, warming to 37 °C and sonicating if needed.
Dihexa is specifically engineered to be orally active and blood‑brain‑barrier‑permeable. For animal research, it is often given orally (2 mg/kg/day) or intraperitoneally (i.p.) after dissolving in DMSO. Your calculator’s injection‑only assumption is incorrect for this compound.
Dihexa is 100 × more potent at binding HGF than standard AngIV. A very low concentration (0.1 μM) can substitute for growth factors in certain assays. However, for synaptogenesis, it works best at very low picomolar to nanomolar concentrations. The calculator’s linear mg‑scale output may ignore the non‑linear, highly potent window of activity.
Yes, but with a nuance. Lyophilised powder is stable at –20 °C for up to 36 months (some sources say 3 years), and at 4 °C for up to 2 years. Avoid moisture. For a stock solution in DMSO, store at –80 °C for 6 months, or –20 °C for 1 month.
No. Reconstituted Dihexa should be stored at 4 °C for only 2‑7 days. For longer storage, freeze the solution at –20 °C (stability of 1‑3 months) and aliquot to avoid multiple freeze/thaw cycles. Adding a carrier protein (0.1% HSA or BSA) is recommended for long‑term freezing.
Practical takeaway: If your real goal is weight or metabolic health, the most useful next step is discussing approved treatment options with a clinician rather than relying on an unapproved compound.
Important: This tool is for informational and research-reference purposes only. Not intended for human or veterinary use.